This clinical study was undertaken to evaluate the antibacterial effects of chemomechanical preparation using nickel-titanium (NiTi) rotary instrumentation with 2.5% NaOCl irrigation, followed by a supplementary final rinse with 2% CHX and one-week interappointment medication with a paste of calcium hydroxide in 2% CHX.
Supplementary steps consisting of a final rinse with CHX followed by calcium hydroxide interappointment medication promoted further decrease of the bacterial bioburden to levels significantly below those achieved by the chemomechanical procedures alone. Because the long-term outcome of root canal treatment is dependent upon maximal bacterial reduction, the present results are of clinical relevance. IEJ 2012
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