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  • #10874
    Drsumitra
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    Registered On: 06/10/2011
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    I would like to know if a patient who is suffering from THALASSEMIA minor or major, can be subject to extraction, or is RCT a better option..

    Also what does one do if the tooth is beyond salvage?

    #15892
    Anonymous

     HI Doctor,

     

          Well patients with Thalassemia Major/Minor generally have their bleeding and clotting time within normal limits. Any invasive Dental procedure should however be planned after these steps:

     

    1. routine Hb, BT, CT, PT, PTT

    2. A written consent from the treating pediatrician/specialist

    3. Perform any procedure on the day of patient’s blood transfusion preferrably while the patient is in day care incase of thalassemia major patients.

         I hope this information was useful. Also you can refer to Little-Textbook for Dental Treatment of Medically Compromised.

    Regards

    Dr Sony

    #15894
    Drsumitra
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     This information was definitely very helpful Dr thank you so much.

    I would like to ask you if you would recommend that any procedure be done in a hospital setup or its safe to conduct it in pvt setup if we have physician consent and blood reports are normal

    #15896
    drmithila
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    some information about blood disorders

    Typically, blood disorders can affect overall oral health, as well as interfere with a number of dental procedures. Therefore, it is always important to let your dentist know if you have blood disorders, as well as information about medications used to treat these conditions.
    Why Procedure is Used
    While most people with blood disorders can see a regular dentist, some may need to go to a specialist. For example, if your platelet range is between 20,000 and 50,000, it will be to your advantage to see a dental specialist. Alternatively, if you have polycytemia vera, or excess red blood cell production, you may need to see a special type of dentist. Aside from helping reduce the risk of clots and bleeding, this type of dentist may also want to monitor your condition with bloodwork. As you may be aware, polycytemia can occur in heavy smokers, as well as individuals that have emphysema. Typically, this illness will cause red or purple regions on the tongue, as well as the lips, gums, and cheeks. Since polycytemia can occur when the body is lacking in oxygen, you may also develop this condition when you move to an area with a higher altitude.
    Patient Concerns to be Addressed
    If you have a low number of neutrophils (neutropenia) in your body, you may have an increased risk of getting bacterial infections. Typically, HIV/AIDS, as well as medications that interfere with the normal function of bone marrow can cause neutropenia. Unfortunately, if you have a mouth infection, the redness and swelling caused by the action of neutrophils may not be present. As may be expected, if you do not monitor your oral health carefully, you may find that gum diseases, thrush, deep mouth sores, and mouth ulcers can get out of control very quickly.
    Aside from a lack of white blood cells, some people are also anaemic. As you may be aware, this condition may result from blood loss, destruction or reduced production of red blood cells, fluid overload, vitamin and nutrient deficiencies, genetic disorders, and issues with hemoglobin molecules. Aside from making the insides of your mouth look pale, your tongue may also be very smooth if you are anaemic. In addition, X-rays may reveal changes in your jawbone.
    Individuals that are haemophiliacs, or have low platelet levels may have issues if they need to undergo procedures that result in bleeding. For example, a haemophiliac may need to take extra treatments to build up certain blood factors prior to dental treatments. In some cases, you may also not be able to tolerate certain kinds of anaesthesia. That said, you should be able to go for common dental procedures such as root canals, fillings, crowns, braces, and denture fittings. On the other hand, it is best to avoid oral surgery as much as possible.
    Depending on the situation, you may also need to have dental procedures in a hospital setting. That said, today many people are able to inject blood factor products on their own. As may be expected, it will be best to discuss these issues with your doctor as well as your dentist. Chances are, your dentist will also want to see your latest bloodwork results in order to learn more about your platelet levels. You may also need to have additional bloodwork in order to determine if you need additional medication prior to certain dental procedures. In particular, if your platelet count goes below 20,000, you may need to have a platelet transfusion.
    How Is Procedure Performed?
    In some cases, people with blood disorders need antibiotics prior to having dental procedures. For example, if your neutrophil count is less than 1,000, or if you have aplastic anaemia, you will most likely need to use antibiotics, as well as use an antibiotic mouthwash. Depending on your blood counts, you may need to take these medications both before and after the procedure. On the other hand, i f you have some form of chronic anaemia, you may also need to have oxygen during certain procedures.
    If you have disorders that would lead to uncontrolled bleeding, your dentist may also use antifibrinolytic medications. You may also need to take additional precautions based on the type of procedure, and the current condition of your blood. As may be expected, if you have sickle cell anaemia, it is best to have your teeth cleaned when the condition is in a dormant period.
    Post-Operative Concerns
    If you have thalassemia, or other types of chronic anaemia, healing may occur very slowly. Therefore, you should always carefully discuss any dental procedures with your dentist and find out how they will affect your blood counts. Even though your dentist will do everything possible to minimize bleeding, there are some things you will also need to be careful of after certain procedures.
    Among other things, if you have braces, you will need to try and prevent cuts from the wires, brackets, and bands. In some cases, it may be better to have braces that attach to your teeth, as opposed to removable versions. For people that have haemophilia, it is also very important to replace blood factors that aid in clotting. Typically, you will need to have at least 50 – 100% of the normal level prior to surgery. As may be expected, you should replace these factors as needed after the procedure. It may also be of some help to eat soft foods, a well as take medication that reduce the chance of blood clots breaking. If you experience pain or discomfort, you will need to avoid aspirin, and other NSAID’s (nonsteroidal anti-inflammatory drugs). This includes Advil, Ibuprofin, Motrin, and other similar painkillers.
    Perils of Disease
    In some cases, individuals with blood disorders such as haemophilia may be afraid to brush their teeth. While brushing can make your mouth bleed more than usual, you should try to observe proper oral hygiene as much as possible. It may also be of some help to ask your doctor for additional suggestions.

     

    #15897
    drmithila
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    SYMPTOMS OF THALASSEMIA PATIENTS:

    1. Thalassemia patients have overactive bone marrow that leads to enlarged and thickened head and face bones. This can lead to deformities of the head and face. For example, the upper and lower jaws are larger than normal. This can lead to problems such as:
    i) Malocclusion
    ii) Enlarged tongue (macroglossi)
    iii) Child patients have the same normal tooth size as other children. However, due to faster rate of growth of the jaw, there may be spacing between their teeth, leading to unsightly appearance.
    – They also have the tendency to have weak arms and legs that fracture easily.
    2. Iron overload
    The treatment for more severe thalassemia is through blood transfusions or bone marrow transplant. Regular blood transfusions can lead to iron overload, which can then lead to cardiac failure, or affect liver and endocrine system. Hence patients undergoing blood transfusion also take iron-chelating agents (such as Desferron) after transfusions to remove excess irons from the body. Desferron can be deposited on skin, thus why some of the thalassemic patients have a grayish appearance of skin.

    3. Other symptoms of anemia such as shortness of breath, fatigue and pallor.
    4. Shortened life span
    -Those with thalassemia minor usually have a normal lifespan, but patients with thalassemia major often have their life shortened due to complications such as heart and liver failure.

     

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