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  • #12244
    Anonymous
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    Worldwide, oral carcinoma is one of the most prevalent cancers and is one of the 10th most common causes of death in all societies, with its relative position varying with age and sex. Cancer is defined as a malignant and invasive growth or tumor, tending to recur after excision and metastasize to other sites. According to the international classification of diseases (ICD) oral cancer is a malignancy arising from the lips and other intraoral sites. It is the sixth most common cancer reported globally with an annual incidence of over 300,000 cases, of which 62% arise in developing countries. Oral cancer is related to the consumption of tobacco, alcohol and other carcinogenic products. It typically occurs in the elderly men during the fifth through eighth decade of life and is rarely seen in young people. Approximately 90% of oral cancers are primary squamous cell carcinomas arising from the lining mucosa of the mouth, most commonly the tongue and the floor of the mouth.

    #17435
    Drsumitra
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    Treatment

    Treatment varies depending on the size, depth, and location of the basal cell cancer. It will be removed using one of the following procedures:

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    Excision cuts the tumor out and uses stitches to place the skin back together.
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    Curettage and electrodesiccation scrapes away the cancer and uses electricity to kill any remaining cancer cells.
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    Surgery, including Mohs surgery, in which skin is cut out and immediately looked at under a microscope to check for cancer. The process is repeated until the skin sample is free of cancer.
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    Cryosurgery freezes and kills the cancer cells.
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    Radiation may be used if the cancer has spread to organs or lymph nodes or for tumors that can’t be treated with surgery.
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    Skin creams with the medications imiquimod or 5-fluorouracil may be used to treat superficial basal cell carcinoma.

    Expectations (prognosis)

    The rate of basal cell skin cancer returning is about 1% with Mohs surgery, and up to 10% for other forms of treatment. Smaller basal cell carcinomas are less likely to come back than larger ones. Basal cell carcinoma rarely spreads to other parts of the body.

    You should follow-up with your doctor as recommended and regularly examine your skin once a month, using a mirror to check hard-to-see places. Call your doctor if you notice any suspicious skin changes.
    Complications

    Untreated, basal cell cancer can spread to nearby tissues or structures, causing damage. This is most worrisome around the nose, eyes, and ears.
    Calling your health care provider

    Call your health care provider if you notice any changes in the color, size, texture, or appearance of any area of skin. You should also call if an existing spot becomes painful or swollen, or if it starts to bleed or itch.
    Prevention

    The best way to prevent skin cancer is to reduce your exposure to sunlight. Ultraviolet light is most intense at midday, so try to avoid sun exposure during these hours. Protect the skin by wearing hats, long-sleeved shirts, long skirts, or pants.

    Always use sunscreen:

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    Apply high-quality sunscreens with SPF (sun protection factor) ratings of at least 15.
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    Look for sunscreens that block both UVA and UVB light.
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    Apply sunscreen at least 30 minutes before going outside, and reapply it frequently.
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    Use sunscreen in winter, too.

    Examine the skin regularly for development of suspicious growths or changes in:

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    Color
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    Size
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    Texture
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    Appearance

    Also note if an existing skin sore bleeds, itches, is red and swollen (inflamed), or is painful.

    #17437
    Anonymous

    Squamous Cell Cancer of the tongue.

    This tumor is usually located on the side, or what we call the lateral border, of the oral tongue. It is usually somewhat ulcerated and is grayish-pink to red in color. It will often bleed easily if bitten or touched. Smoking and drinking are known to contribute to the formation of the cancers, although some folks have developed squamous cancer of the tongue with no known extra risk factors.

    Most very small cancers of the oral tongue can be quickly and successfully treated by surgical removal leaving behind little cosmetic or functional change. THIS IS NOT ALWAYS TRUE, HOWEVER, AS THERE CAN BE MANY VARIABLES AND FACTORS THAT CAN SERIOUSLY IMPACT SPEECH AND SWALLOWING. This can only be assessed by a face to face Surgeon/Patient meeting and examination.

    Larger cancers may indeed have some effect on speech and on swallowing, but one must remember that not treating this problem would cause far more significant problems, up to, and including death. If one thinks about that for a moment; a few changes in speech or swallowing seem like a pretty good swap.

    There is a school of thought that small oral tongue cancers can be better managed by radiation therapy alone, and this is indeed true in some cases, especially where the patient has serious heart and/or lung disease that might make anesthesia risky. Fortunately, this is a rare occurrence.

    The main reason for treating small sqamous cancer of the oral tongue with surgery is that it is at least as curative as radiation, possibly better, it is over with quickly, oftentimes done as an out patient procedure instead of 5 – 6 weeks of daily therapy, it may be significantly less expensive, and finally, and most importantly, it means that if a patient were to later present with a 2nd or 3rd Squamous Cell Cancer of the mouth/throat/or voice box area, you would still have radiation therapy as a treatment option, perhaps then being able to avoid a significant and disfiguring operation. There is a limit as to how much radiation normal tissue can take before it dies.

    Some cases of Oral Tongue Cancer can be treated with just removal of the primary tumor in the tongue. But as the size of the primary tumor increases the statistical possibility of some cancer cells spreading through lymphatic vessels to the lymph nodes of the neck increases. The site and pattern of the involved lymph nodes is pretty much constant — that is to say we know where in the neck to look for enlarged lymph nodes that might contain metastatic cancer cells from the oral tongue cancer. Exceptions to these rules are sometimes seen, but they are uncommon. When the presence of enlarged lymph nodes in the neck is detected or when the index of suspicion is high that there may be cancer cells present in lymph nodes, then an operation called a neck dissection is performed to remove these "secondary" deposits of cancer. Remember, the oral tongue cancer is the "primary" tumor from where the spreading cells originate.

    There are many forms of neck dissections from radical to conservative While many physicians may have had some exposure to neck dissections at some point in their career, there are very few Head and Neck Surgeons, usually found in large medical centers, who can truly say that their career has been dedicated to this type of disease and they have done hundreds or perhaps thousands of these procedures.
    Finally, there may sometimes be the need to perform plastic surgery and/or reconstruction following removal of the tumor, and radiation treatments may have to be given after the surgery to try to minimize the possibility of recurrence of the disease and ultimate treatment failure. Yes, sometimes in spite of every effort, every bit of hard work, in spite of supportive care and even our prayers, some patients will be lost to this disease. It is a sad thing to have to watch and be a part of, but it is one of life’s unpleasant realities. For now, we will have to content ourselves with the knowledge that most of our tongue cancer patients survive quite nicely and hope that new research and new discoveries in the future will allow us to help our patients even more.

    #17438
    Drsumitra
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    Squamous Cell Cancer of the base of tongue

    Like the oral tongue, the base of tongue (or posterior 1/3) can also grow several types of cancers, but again, squamous cell carcinoma is the most common and we will direct our comments with that in mind.Unlike oral tongue cancers, base of tongue squamous cell cancer is usually larger when diagnosed because in the early stages it can not be seen and it creates few, if any, symptoms. Later however, base of tongue cancer may create pain, a sense of fullness, changes in what the voice sounds like, and perhaps even some difficulty in swallowing. Also, because the diagnosis often comes a bit later, a greater number of patients with this disease will already have neck metastasis, that is, cancer cells in the lymph nodes of the neck, by the time they are seen by the Head and Neck Surgeon.

    While it may technically feasible to surgically remove some base of tongue cancers, it is our opinion that most can and should be treated by radiotherapy. These tumors are arguably more sensitive to radiation treatment than some other cancers. Certainly, there are exceptions to this. Radiation therapy can also be used to control the cancer in the neck nodes as long as it is not too advanced. Interestingly, in those cases, we will sometimes remove massive neck node disease before starting radiation therapy when we know that x-ray therapy alone would not be successful in controlling the neck disease.

    The prognosis after treatment of base of tongue cancer will vary from patient to patient as with any type of malignant disease. It has been our experience that the cure rate is good, but not quite as good as for early detected oral tongue cancer. The fact that base of tongue cancers are usually larger at the time of diagnosis probably is a significant contributing factor to this disparity. Very large base of tongue cancer may require a combination of surgery and radiation

    #17441
    sushantpatel_doc
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    BASAL CELL CARCINOMA
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    #17444
    sushantpatel_doc
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    Is it true that eating hot and spicy food predisposes to tongue cancer?

    #17445
    Anonymous

    The precise mechanism by which spices prevent the development of cancer is not well understood. Spices are some of the best natural anti-oxidants, and may be acting by protecting the cells from DNA damage. There is a documented association between germs and cancer; estimates are that ~15% of cancers globally are caused by micro-organisms. It is possible that many cancers are initiated by pathogens and spices prevent this from happening by killing off the germs. More importantly, natural substances like onion, garlic, ginger, turmeric, red chilly, tomatoes, and black pepper have now been scientifically proven to interfere with the very intracellular signaling which accounts for the excessive proliferation and loss of maturation in cancer cells. The bio-chemical properties of these substances are being widely investigated now, with over 1000 papers published in highly respected medical journals on curcumin and ginger in the last few years alone.

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