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Salivary gland neoplasms are classified by the World Health Organization as primary or secondary, benign or malignant, and by tissue of origin. This system defines five broad categories of salivary gland neoplasms:
malignant epithelial tumors (e.g. acinic cell carcinoma, mucoepidermoid carcinoma and adenoid cystic carcinoma, salivary duct carcinoma)
benign epithelial tumors (e.g. pleomorphic adenoma, myoepithelioma and Warthin tumour, sebaceous lymphadenoma)
soft tissue tumors (Hemangioma)
hematolymphoid tumors (e.g. Hodgkin lymphoma)
secondary tumors.
Signs and symptoms
The most common symptom of major salivary gland cancer is a painless lump in the affected gland, sometimes accompanied by paralysis of the facial nerve.
Treatment
Surgery
Radiotherapy
Fast neutron therapy has been used successfully to treat salivary gland tumors and has shown to be significantly more effective than photons in studies treating unresectable salivary gland tumors.