Early detection of oral cancer: PAP and AgNOR staining in br

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This topic has 2 replies, 3 voices, and was last updated 19/01/2011 at 5:05 pm by Anonymous.

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19/11/2010 at 7:42 am #9738

tirath
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brush biopsy in conjunction with AgNOR staining is an easily practicable, non-invasive, safe and accurate screening method for the detection of macroscopically suspicious oral cancerous lesions. Because of its simple technique and high reliability for cellular proliferation, AgNOR staining in brush smears can be used as an adjunct to other routine cytological diagnoses for the early detection of oral cancer.



20/11/2010 at 6:19 pm #14397

sushantpatel_doc
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Can this test be done in a clinical set up?



19/01/2011 at 5:05 pm #14398

Anonymous

Its difficult to use AgNOR’s in a clinical set up as compared to PAP coz AgNOR is quite technique sensitive, cannot reuse, it is costly & for cytology, many slides cannot be stained once coz it depends on the inflow of the patient that day & the slides need to be fixed, fixation can vary for different slides.
other option is MGG.
any other stain that can be used?
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