Periodontitis And Myocardial Infarction: A Shared Genetic Pr

[drsushant]

 IMPACT OF SYSTEMIC DRUG MANAGEMENT ON PERIODONTAL HEALTH 

In March 2011, Payne et al¹⁶ completed a 2-year study using SDD to reduce systemic biomarkers including serum inflammatory MMP and high sensitivity C-reactive protein (hsCRP). There was also a statistically significant increase in high-density lipoprotein (good) cholesterol in women more than 5 years postmenopausal. Alveolar bone density loss was reduced. Clinical attachment levels were stabilized. SDD and periodontal maintenance decreases the odds of more progressive periodontitis by 19% relative to placebo.
Ridker et al¹⁷ did significant research to identify hsCRP as a systemic inflammatory biomarker, reporting it to be more predictive of cardiovascular events than elevated low-density lipoprotein cholesterol levels.

LOCAL DELIVERY OF SITE-SPECIFIC ANTIMICROBIAL DRUGS 
The local delivery of antimicrobials, such as Arestin (Orapharma), offer the dentist a statistical and significant system for the treatment of periodontitis.18 The Agency for Health Care Research and Quality (the federal agency assigned to improve quality, safety, efficiency, and effectiveness of healthcare) evaluated literature on these antimicrobials in 2004.¹⁹ They concluded that scaling/root planing, when accompanied by the placement of an antimicrobial agent (Arestin) as a supplement or adjunct treatment, resulted in an improved clinical outcome in adults with chronic periodontitis. (This was compared to scaling/root planing that was done alone.) Systemic and locally placed antimicrobial drugs are therefore suggested for use when active disease is detected. They have clearly shown in the studies mentioned to be of significant help in resolving the diseased condition and restore periodontal health as quickly as possible. 
Patients usually understand medical treatment with medication. It is a natural addition to periodontal treatment, following the medical model. These drugs can be used on a routine basis as a standard of care, in successfully managing periodontal disease.