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03/05/2011 at 4:00 pm
#17170
Anonymous
ANTIBIOTIC REGIME FOR TREATMENT
most authors recommend penicillin + metronidazole. Agents used empirically to cover predominant organisms. Use tissue/blood cxs to tailor regimen. Rx for at least 14 days.
* Preferred: penicillin G 2-4 million U IV q4h + metronidazole (Flagyl) 500mg IV q6-12h.
* Alternative: ampicillin/sulbactam (Unasyn) 3.0g IV q6h.
* PCN allergy: clindamycin (Cleocin) 600mg IV q8h.
* Note: use of systemic abx in HIV pts may cause candidal overgrowth requiring additional antifungal coverage. Consider Nystatin rinses 5ml four times a day or fluconazole 200mg PO once daily.