Healthy children under 36 months of age, presenting early childhood caries were randomly assigned to receive protective stabilization plus: combined oral midazolam (0.5 mg/kg) and ketamine (3 mg/kg) (MK), or oral midazolam (1.0 mg/kg) (MS), or no sedative (PS).
The combination of oral midazolam and ketamine is efficacious for guiding the behaviour of children under 3 years old. (International Journal of Paediatric Dentistry)
