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Aprotinin reduces blood loss and the need for transfusionin

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  • 17/01/2011 at 12:47 pm #9911
    tirathtirath
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    Registered On: 31/10/2009
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    randomized, placebo-controlled, double-blind trial showed that patients given aprotinin intravenously (200 ml, [2000000 kallikrein inactivator units] before the operation and then 50 ml per h until the end of the operation) during simultaneous maxillary Le Fort 1 and mandibular sagittal split osteotomies, lost 52% less blood than controls (calculated by subtracting the volume of saline irrigant used from the volume of blood collected in the aspirator bottle and surgical drains)

            

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